infoRouter needs to create temporary files during uploads, downloads and searching. This temp folder is checked at application startup to make sure it can be accessed and read from.
If you are getting this message, this is more than likely due to insufficient permissions assigned to infoRouter.
Locate your temporary directory and make sure infoRouter has proper access to this folder.
On IIS 6 (Windows 2003) the Network Service account temporary folder is located under the WINDOWS\tmp folder. This temporary folder used for uploads.
Make sure the path specified in the error exists and the ASPNET or the NETWORK SERVICE account has Full Control permissions to this path.
On Windows 2003 make sure that the NETWORK SERVICE has Full Control to the C:\Windows\tmp directory.